Use with benzodiazepines or other CNS depressants including other opioids, nonbenzodiazepine sedative/hypnotics, anxiolytics, general anesthetics, muscle relaxants, antipsychotics, and alcohol may cause profound sedation, respiratory depression, coma, and death reserve concurrent use for when alternative treatment options are inadequate. ![]() Drugs that affect serotonergic neurotransmitter systems, including tricyclic antidepressants, SSRIs, SNRIs, MAO inhibitors, TCAs, tramadol, trazodone, mirtazapine, 5–HT 3 receptor antagonists, linezolid, methylene blue, and triptans ↑ risk of serotonin syndrome.
0 Comments
Leave a Reply. |